The .NET embedded machine agent reports hardware metrics such as:
When IIS is installed on the machine, the .NET machine agent also reports IIS, ASP.NET and ASP.NET Application metrics. See Monitor IIS.
The App Agent for .NET reports CLR metrics, which are also based on MS Performance Counters. See Monitor CLRs.
If you install the Standalone Machine Agent, which is a Java application, in a .NET environment, then you can add custom monitors and extensions such as the HTTP listener. See Standalone Machine Agent for details.